AsurDx™Japanese Encephalitis (JEV) Antibody Test Kit

The AsurDxTM Japanese Encephalitis (JEV) Antibody Test Kit is designed for the detection of pig antibodies specific to Japanese Encephalitis Virus (JEV)

Feature


  • Detects antibodies against JEV in pig serum/plasma;
  • Procedures last less than 2 hours;
  • Provides a simple, rapid, sensitive, and cost-effective enzyme-based immunoassay (ELISA) screening method

*Availability/Distribution: Product is designed and developed by BioStone US Texas headquarter and manufactured/assembled by BioStone oversea subsidiaries or partners. Currently, the product is only available outside of the USA. Regulatory requirements vary by oversea countries; the product may not be available in your geographic area.

Specification


Method Colorimetric ELISA
Coated AntigenRecombinant JEV proteins
Incubation Time85 minutes
StorageAt least 12 months
SpecificityJEV specific pig antibodies

Order Information


Catalog Number10100-0210100-05
Plates2 plates5 plates
Reactions192480
Plate Format12 X 8-well strips12 X 8-well strips

About Disease


JEV is a flavivirus which is closely related to Dengue virus, West Nile virus, and Zika virus. The disease was first identified in Japan in the late 1800s, and is endemic to Asia and the Pacific, including Australia. It is spread through mosquito bites, especially of the Culex, Aedes, and Anopheles genera, and can infect many animals, including pigs, horses, goats, sheep, cattle, water birds, and humans.  While most hosts are dead end carriers who are unable to pass infections back to mosquitoes, the virus can be spread back to mosquitoes in pigs, which can transmit the virus to other pigs. Mosquitoes can be carried long distances by win or hitchhiking on migratory birds.  The main method of control is mosquito control, although recently a swine vaccine based on a chimeric hybrid virus has been developed in Australia. However, the efficacy of the vaccines are not certain, and there are currently no treatments for the disease in infected pigs.

JEV usually causes no symptoms in adult sows, but the virus can be transmitted by pregnant females to piglets.  Infection before 70 days of gestation can result in stillbirth, miscarriage, or severe birth defects in piglets such as hydrocephalus, cerebellar hypoplasia, subcutaneous edema, and hepatic and splenic necrosis.  Infection in boars can lead to testicular edema, reduced sperm motility, and temporary infertility.  The disease is widespread in pigs, in India 7% of pigs were identified as carriers.  The virus is transmitted to humans by mosquitoes feeding on infected pigs, causing an estimated 70,000 cases annually.  The disease is fatal in 20-30% of human cases, and 50% of survivors develop long term neurological defects.