AsurDx™ CAEV/MVV Antibody Test
The AsurDxTM CAEV/MVV Antibody Test Kit is designed for the detection of antibodies specific to caprine arthritis encephalitis virus (CAEV) in goat serum/plasma and Maedi-visna virus (MVV) in sheep serum/plasma.
Feature
- Detects CAEV/MVV IgG antibodies in serum/plasma of goats and sheep;
- Procedures last less than 120 minutes;
- Provides a simple, rapid, sensitive, and cost-effective enzyme-based immunoassay (ELISA) screening method
*Availability/Distribution: The product is designed and developed by BioStone US Texas headquarters and manufactured/assembled by BioStone oversea subsidiaries or partners. Currently, the product is only available outside of the USA. Regulatory requirements vary by oversea countries; the product may not be available in your geographic area.
Specification
| Method | Indirect ELISA |
| Coated Antigen | CAEV/MVV Antigen-Coated Plate |
| Incubation Time | 120 minutes |
| Storage | At least 12 months |
| Specificity | Detect CAEV/MVV IgG antibodies in serum/plasma of goat and sheep |
Order Information
| Catalog Number | 10097-02 | 10097-05 |
| Plates | 2 plates | 5 plates |
| Reactions | 192 | 480 |
| Plate Format | 12 X 8-well strips | 12 X 8-well strips |
About Disease
CAEV manifests itself in adult goats mainly in the form of severe arthritis of the carpal joint (“big knee”). Animals with CAEV become emaciated despite an intact appetite and show poor milk yield. Serologic surveys show that CAEV is widely disseminated in goat herds on different continents. MVV infection of sheep is characterized by slowly progressive arthritis, pneumonia, mastitis, and encephalomyelitis. MVV infection is found all over the world.
Maedi-visna and caprine arthritis and encephalitis are economically important viral diseases that affect sheep and goats. These diseases are caused by a group of lentiviruses called small ruminant lentiviruses (SRLVs). SRLVs include maedi- visna virus (MVV), which mainly occurs in sheep, and caprine arthritis encephalitis virus (CAEV), mainly found in goats, as well as other SRLV variants and recombinant viruses. The causative viruses infect their hosts for life, most often subclinically; however, some animals develop one of several progressive, untreatable disease syndromes. The major syndromes in sheep are dyspnea (maedi) or neurological signs (visna), which are both eventually fatal. Adult goats generally develop chronic progressive arthritis, while encephalomyelitis is seen in kids. Other syndromes (e.g., outbreaks of arthritis in sheep) are also reported occasionally, and mastitis occurs in both species. Additional economic losses may occur due to marketing and export restrictions, premature culling, and/or poor milk production. Economic losses can vary considerably between flocks.